Computer-aided design (CAD) models serve as the starting point for microfluidic applications.
To enhance accessibility and accelerate the adoption of microfluidics, we have generated
and compiled a library of common microfluidic CAD designs in their native file formats.
Disclaimer: Please note, this content is for non-commercial use only, and we do not guarantee the performance of any of the files. CAD files linked to external websites are subject to their respective terms and conditions.
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Filters for Design, Application, and Fabrication
Filters are included by general design, application, and fabrication method. F3D files are native CAD files with full design trees and CNC-based files have CAM programmed for user reference. Download DWG files and view using an online tool like ShareCAD and use 3DViewer for STL files.
- Female Luer Lock Port by ELEXAN Scientific (3D Printing)
Description: General female luer lock port.
F3D Download (3D Preview: Link)
- Circle Profile Threaded Port by ELEXAN Scientific (3D Printing)
Description: 1/4-28 female threads with circular body.
F3D Download (3D Preview: Link)
- Square Profile Threaded Port by ELEXAN Scientific (3D Printing)
Description: 1/4-28 female threads with square body.
F3D Download (3D Preview: Link)
- Luer Fitting Generator Plugin for Autodesk Fusion by Ortus Lab (3D Printing)
Description: Handy plugin for Autodesk Fusion to generate female and male luer interfaces.
Autodesk Plugin Download
- Configurable Single Channel with Luer or Threaded Ports by ELEXAN Scientific (3D Printing)
Description: User-editable Fusion file for single-channel microfluidic chip (75 mm Length X 25 mm Width). Luer and threaded ports can be supressed and unsupressed based off user's preference.
F3D Download (3D Preview: Luer, Threaded)
- Configurable Single Channel by ELEXAN Scientific (CNC)
Description: User-editable Fusion file for single-channel microfluidic chip (75 mm Length X 25 mm Width). CNC CAM programs are included.
F3D Download (3D Preview: Link)
- Configurable Flow Cell with Luer or Threaded Ports by ELEXAN Scientific (3D Printing)
Description: User-editable Fusion file for microfluidic flow cell chip (75 mm Length X 25 mm Width). Luer and threaded ports can be supressed and unsupressed based off user's preference.
F3D Download (3D Preview: Luer, Threaded)
- Configurable Flow Cell by ELEXAN Scientific (CNC)
Description: User-editable Fusion file for microfluidic flow cell chip (75 mm Length X 25 mm Width) with CAM setup.
F3D Download (3D Preview: Link)
- Blank Chip with Luer or Threaded Ports by ELEXAN Scientific (3D Printing)
Description: Fusion file for blank microfluidic chip (75 mm Length X 25 mm Width). Can be used as starting template to design features onto chip bottom. Can also be assembled to microscope slides using double-sided adhesive patterned with channels or chambers for quick flow cell.
F3D Download (3D Preview: Luer, Threaded)
- Component library creation and pixel array generation with micromilled droplet microfluidics
Description: CNC CAD files from Densmore Lab with designs to CNC mill droplet generator, picoinjector, detector and sorter with carbon paste electrodes. CAM is programmed.
F3D Download (DOI: Link)
- A bead-based method for high-throughput mapping of the sequence- and force-dependence of T cell activation
Description: Nature Methods protocol from Fordyce Lab with microwell array to capture spectrally encoded hydrogel beads captured with T-cell to explore mechanical effects on T-cell activation. Beads made using MRBLES technology.
OSF Repository (DOI: Link)
- Engineered human blood–brain barrier microfluidic model for vascular permeability analyses
Description: Nature Methods protocol with popular microfluidic design by Kamm Lab for vessels on a chip. Microfluidic mask design for soft lithography.
DWG Download (DOI: Link)
- Engineered human blood–brain barrier microfluidic model for vascular permeability analyses
Description: Nature Methods protocol with popular macrofluidic (larger) design by Kamm Lab for vessels on a chip for 3D printing fabrication techniques.
STL Download (DOI: Link)
- Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
Description: Popular drop-seq design from McCarroll lab with over 7500 citations.
DWG Download (DOI: Link)
- High-Throughput Affinity Measurements of Affinity and Specificity Determinants Transcription Factor and DNA Mutations Reveal Affinity and Specificity Determinants
Description: Microfluidic design containing over 1500 microchambers for high-throughput screening of transcription factor variants.
DWG Download (DOI: Link)
- Double emulsion picoreactors for high-throughput single-cell encapsulation and phenotyping via FACS.
Description: Dropception double-emulsion droplet design from Fordyce Lab. Dots embedded in channels are part of the mask design. 2-layer photoresist fabrication.
OSF Repository (DOI: Link)
- MRBLES 2.0: High-throughput generation of chemically functionalized spectrally and magnetically-encoded hydrogel beads using a simple single-layer microfluidic device.
Description: Parallel flow focusing device to generate droplets then polymerized off-chip to yield hydrogel beads. Design from Fordyce Lab.
OSF Repository (DOI: Link)
- Review: Syringe Pump vs Pressure Controller for Microfluidic Droplet Generation
Description: Dual-inlet droplet generator design used to evaluate setting up syringe pump vs Elveflow.
F3D Download (3D Preview: Link)
- CNC Machining Microfluidics: Milling a Microfluidic Droplet Generator Chip
Description: Demo file used to demonstrate how to CNC machine a microfluidic droplet generator using an affordable router. CAM programs in Fusion file.
F3D Download (3D Preview: Link)
- Mask with 76 different micropillar designs.
Description: Mask for micropillars with varying diameters and spacing. Includes crescent and oval geometries. Can be used for various applications. Open in AutoCAD.
ELEXAN Scientific Folder
- Low-cost inertial microfluidic device for microparticle separation: A laser-Ablated PMMA lab-on-a-chip approach without a cleanroom
Description: Single channel sorter to separate particles of different sizes fabricated from laser-cut PMMA.
Original DWG by Authors; F3D Download by ELEXAN Scientific (DOI: Link, 3D Preview: Link)
- Mask with 76 different hollow microcylinder designs.
Description: Mask for hollow microcylinder pattern with varying diameters and spacing. Includes ovals. Can be used for various applications. Open in AutoCAD
ELEXAN Scientific Folder
- Mask with dielectrophoresis electrodes and flow cell overlay.
Description: Mask with various dielectrophoresis electrodes and flow cell overlay. 2-separate masks. Requires multi-step fab.
ELEXAN Scientific Folder
- CAD Tools from CIDAR
Description: CIDAR Lab’s list of open-source microfluidic CAD tools.
CIDAR Webpage
- FLUI’DEVICE by EDENTECH
Description: Drag-and-drop microfluidic CAD with built-in fluid pressure calculator. Some features require a paid license.
FLUI’DEVICE Webpage
